Microneedling with polynucleotides | Why September is the perfect time for a skin reset

After a summer of sun, heat, travel and disrupted routines, September is often when skin starts to show the effects.

You may notice that your complexion feels drier, looks duller or has become more uneven in texture. Fine lines can appear more noticeable, pigmentation may feel more obvious and skin can simply look less fresh than it did earlier in the year.

At Beverley Alexandra in Ramsbottom, one of the treatments we are focusing on this autumn is microneedling with polynucleotides delivered via mesotherapy — a combination designed to support skin quality, hydration and collagen stimulation rather than simply masking the signs of tired or ageing skin.

It is less about chasing an instant “glow” and more about creating healthier-looking skin over time.

What is microneedling with polynucleotides?

Microneedling and polynucleotides work in different but complementary ways.

Microneedling uses very fine needles to create controlled micro-channels in the skin. This controlled injury stimulates the skin’s natural repair response and is associated with collagen production and tissue remodelling. Clinical reviews have found microneedling to be a useful treatment for concerns including skin texture, photoageing, wrinkles and scarring, although protocols and results vary between patients.

Polynucleotides are injectable compounds made from chains of nucleotides. In aesthetic medicine, they are used to support skin rejuvenation and have been associated with improvements in hydration, elasticity, skin texture and wrinkle appearance. However, the evidence base is still developing, and published reviews emphasise that more high-quality research is needed to define their optimal use.

The polynucleotides can then be delivered using a mesotherapy technique, placing the product superficially within the skin. This allows Bev to tailor the treatment depending on the client’s skin quality, age and concerns, rather than using exactly the same approach for everybody.

Why combine microneedling and polynucleotides?

The thinking behind the combination is that each element supports a different part of the skin-renewal process.

Microneedling creates controlled stimulation within the skin, encouraging a repair response and remodelling of the extracellular matrix. Polynucleotides are then used with the aim of supporting hydration and the wider regenerative environment within the skin. Current literature suggests polynucleotides may support tissue remodelling and hydration, although evidence remains less established than for some longer-standing aesthetic treatments.

For more mature skin, Bev may use microneedling alongside mesotherapy delivery of the polynucleotides. Mesotherapy involves a series of very superficial injections into the skin, allowing the polynucleotides to be placed where they can support hydration and overall skin quality.

For clients, the appeal is that the treatment is focused on skin quality rather than facial volume.

That can make it particularly relevant if your concern is not that you want to look “different”, but that your skin feels:

• Dull
• Dehydrated
• Uneven in texture
• Less firm than it used to
• Crepey
• Tired-looking
• Marked by fine lines
• Affected by post-summer sun exposure or environmental stress

Is this the same as filler?

No.

Dermal filler is primarily used to restore or enhance volume, shape and structure.

Microneedling with polynucleotides is focused more on the condition and quality of the skin itself.

For some clients, filler may still be the right treatment. For others, particularly where the concern is texture, hydration or overall skin quality, a regenerative or skin-focused approach may be more appropriate.

That is why consultation is important. At Beverley Alexandra, treatments are selected according to the individual rather than simply following trends or automatically treating the area a client initially asks about.

What skin concerns can microneedling with polynucleotides help with?

Depending on the individual, the treatment may be considered for concerns such as:

Dull or tired-looking skin

Skin can lose some of its brightness after summer, particularly following periods of sun exposure, dehydration or disrupted skincare routines.

Microneedling aims to stimulate renewal, while polynucleotides are used with the aim of improving hydration and skin quality.

Uneven texture

Microneedling is commonly used to address uneven skin texture and has also been studied in relation to acne scarring and photoageing.

Fine lines

Both microneedling and polynucleotide treatments have been studied in the context of facial rejuvenation and fine lines, although results vary and neither should be presented as an instant or guaranteed correction.

Dehydrated skin

Polynucleotides have been associated with improvements in skin hydration in published aesthetic studies and reviews.

Loss of elasticity

Some studies have reported improvements in skin elasticity following polynucleotide treatment, while microneedling is used to encourage collagen-related remodelling.

Why is September a good time to focus on your skin?

We often think of January as the time to reset, but for skin, September can make just as much sense.

Summer can bring increased UV exposure, heat, dehydration, travel and changes to your normal skincare routine. By early autumn, clients often become more aware of:

• Pigmentation
• Dryness
• Rougher texture
• Fine lines
• Loss of radiance
• General skin fatigue

September also gives you time to begin a treatment plan before the Christmas and party season.

This is important because treatments that aim to support collagen and skin quality are generally not about instant transformation. They work better when viewed as part of a plan.

Good skin in December starts earlier than December.

How many treatments will I need?

There is no single correct answer for everyone.

Microneedling is frequently performed as a course rather than a one-off procedure, and research into facial rejuvenation has commonly involved multiple sessions.

The number and timing of treatments will depend on:

• Your starting skin condition
• Your main concerns
• Your age and skin quality
• Previous treatments
• The area being treated
• Your wider treatment plan

At Beverley Alexandra, the aim is to create a treatment plan based on the individual rather than prescribing the same course to everyone.

When will I see results?

This is not usually an instant-result treatment.

You may notice improvements in how hydrated or fresh the skin appears first, while changes associated with collagen remodelling can take longer to develop.

The key is to think of this as progressive skin improvement rather than a dramatic overnight change.

What is the downtime?

Downtime can vary according to the depth of treatment and the individual.

After microneedling, temporary redness, warmth, sensitivity or mild swelling can occur. Reviews of microneedling report transient redness as one of the more common short-term effects.

Polynucleotide treatments can also cause temporary swelling, redness or small bumps at injection points.

Beverley Alexandra currently advises around one day of recovery for its polynucleotide treatment, with mild discomfort and slight swelling or redness listed as possible side effects.

Your practitioner will explain what to expect based on the treatment being performed.

Is microneedling with polynucleotides suitable for everyone?

No aesthetic treatment is suitable for everybody.

A consultation is important to assess:

• Your skin
• Medical history
• Current skincare
• Previous aesthetic treatments
• Your goals
• Whether this treatment is genuinely the most appropriate option

There may be situations where another treatment is better suited to your concern.

That is central to the approach at Beverley Alexandra: the right treatment is more important than simply having the treatment you originally had in mind.

Where can I have the treatment?

Beverley Alexandra offers advanced skin and aesthetic treatments from its clinic at Brook Bottom Farm in Ramsbottom, serving clients from Ramsbottom, Bury, Rossendale, Rochdale and the surrounding areas. The clinic’s wider Skin Journey includes treatments such as polynucleotides, Profhilo, Profhilo Structura and Sculptra, with needling, microneedling and microdroplet injection techniques used as appropriate.

The September skin reset

If your skin feels as though summer has caught up with it, September is a useful point to reassess.

Rather than looking for a quick fix, the focus should be on understanding what your skin actually needs and building a plan around that.

Microneedling with polynucleotides can form part of that approach, particularly for clients looking to improve skin quality, texture and hydration without adding volume or changing the shape of the face.

To find out whether microneedling with polynucleotides is suitable for you, book a consultation with Beverley Alexandra in Ramsbottom.